Determining Vitamin D Status: A Comparison Between Diabetic And Non-diabetic Women With Breast Cancer By RP-HPLC

Authors

Santosh Gunasekaran, JSS Academy Of Higher Education and ResearchFollow
Suma M. Natraj, JSS Academy Of Higher Education and ResearchFollow
Prashanth Kumar M V, JSS Academy of Higher Education and ResearchFollow

Abstract

Background:

Suboptimal levels of Vitamin D, remains a common problem worldwide and its prevalence is high in India, ranging from 70-100%. Several molecular mechanisms have been found about the effects of Vitamin D in modulating glycemic levels and its protective nature in the development of breast cancer. Breast cancer in India is a common problem and studies regarding its association with Vitamin D levels among diabetics remain inconclusive. This study aims to find the association between Vitamin D status and breast cancer in diabetic and non-diabetic women.

Materials and methods:

25 hydroxy vitamin D levels were estimated by RP-HPLC. A total of 25 serum samples were analysed (20 Breast cancer patients+5 normal).

Results:

Serum sample analysis report of breast cancer patients (irrespective of diabetic status) showed 50% low Vitamin D compared to normal individuals.

Conclusions:

Vitamin D deficiency is very common among women suffering from breast cancer. Although diabetic breast cancer women have lower Vitamin D levels when compared to non-diabetic women, the results in this study are not statistically significant.

First Page

1

Last Page

15

Conflict of Interest

Nil

Keywords

Vitamin D, Breast Cancer, Diabetes

Word Count

2318

Recommended Citation

Gunasekaran S, Natraj SM, Kumar M V P. Determining Vitamin D Status: A Comparison Between Diabetic And Non-diabetic Women With Breast Cancer By RP-HPLC. Digital Journal of Clinical Medicine. 2022; 4(1): 1-15. doi: https://doi.org/10.55691/2582-3868.1002

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Cover Page Footnote

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