Article Title

Determining Vitamin D Status: A Comparison Between Diabetic And Non-diabetic Women With Breast Cancer By RP-HPLC

Authors

Santosh Gunasekaran, JSS Academy Of Higher Education and ResearchFollow
Suma M. Natraj, JSS Academy Of Higher Education and ResearchFollow
Prashanth Kumar M V, JSS Academy of Higher Education and ResearchFollow

Abstract

Background:

Suboptimal levels of Vitamin D, remains a common problem worldwide and its prevalence is high in India, ranging from 70-100%. Several molecular mechanisms have been found about the effects of Vitamin D in modulating glycemic levels and its protective nature in the development of breast cancer. Breast cancer in India is a common problem and studies regarding its association with Vitamin D levels among diabetics remain inconclusive. This study aims to find the association between Vitamin D status and breast cancer in diabetic and non-diabetic women.

Materials and methods:

25 hydroxy vitamin D levels were estimated by RP-HPLC. A total of 25 serum samples were analysed (20 Breast cancer patients+5 normal).

Results:

Serum sample analysis report of breast cancer patients (irrespective of diabetic status) showed 50% low Vitamin D compared to normal individuals.

Conclusions:

Vitamin D deficiency is very common among women suffering from breast cancer. Although diabetic breast cancer women have lower Vitamin D levels when compared to non-diabetic women, the results in this study are not statistically significant.

Conflict of Interest

Nil

Word Count

2318

Recommended Citation

Gunasekaran, Santosh; Natraj, Suma M.; and Kumar M V, Prashanth (2022) "Determining Vitamin D Status: A Comparison Between Diabetic And Non-diabetic Women With Breast Cancer By RP-HPLC," Digital Journal of Clinical Medicine: Vol. 4: Iss. 1, Article 3.