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This article presents a case study of a 4-month-old female baby with combined immunodeficiency syndrome complicated by bilateral otomastoiditis, right-sided parotitis, and facial nerve palsy. The patient presented with symptoms of fever, cold, earache, and ear discharge. Clinical examination revealed redness and swelling in the post-auricular region, along with bloody discharge from the right ear. Further investigations, including blood tests, culture sensitivity, ultrasound scans, and imaging studies, confirmed the diagnosis. The patient was treated with appropriate antibiotics, antifungals, and supportive care. The article discusses the challenges in diagnosing and managing primary immunodeficiency diseases (PIDs), emphasising the importance of early recognition and appropriate treatment. It also highlights the association between recurrent parotitis and immunological factors and the need for further investigations to study this condition. Additionally, the article emphasises the significance of Ig replacement therapy in managing PID patients with significant antibody production disorders. Otolaryngologists play a crucial role in identifying and managing PID patients, contributing to improved outcomes and quality of life for these individuals. Overall, this case underscores the importance of considering combined immunodeficiency syndromes in the differential diagnosis of paediatric patients presenting with recurrent infections, chronic otitis media, and parotitis, and highlights the need for further research in this area.

Publication Date

Summer 6-8-2023


JSS Academy of Higher Education & Research

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Combined immunodeficiency syndrome, otomastoiditis, parotitis, facial nerve palsy, recurrent infection

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Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.



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