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Introduction: Chronic kidney disease (CKD) is one of the leading causes of morbidity and mortality worldwide. CKD and Peripheral arterial disease both independently increase the risk for cardiovascular disease (CVD) events and contribute significantly to morbidity and mortality. There is limited data about the co-relation between ultrasound measures of the femoral artery in peripheral vascular disease (PVD) & renal functional status. This research hence will help us in the establishment of a relationship between femoral intima-media thickness (fIMT) with CKD. Also, IMT assessment might help in earlier detection of atherosclerotic plaques & hence PVD.
Materials and methods: A cross sectional study was conducted for 1 year in a tertiary care hospital. 99 CKD patients with no history of smoking & hypertension were enrolled, who underwent femoral Doppler ultrasonography. The findings of ultrasonography were analysed. Descriptive analysis was carried out for the quantitative data.
Results: The mean age was 52.42 ±15.95years, mean femoral intima media thickness (fIMT) was 0.08± 0.02cm and mean estimated glomerular filtration rate (eGFR) was 17.44±15.44ml/min/1.73m2. In this study men were more commonly affected, most vulnerable age being >60 years. Out of 99 subjects, 69 had raised IMT and 30 patients had normal IMT. Prevalence of atherosclerosis in the given study group was found to be 69.70 %. Higher prevalence of raised IMT among diabetics (75.0%) was present. Not all CKD groups had significant co-relation with IMT.
Conclusion: Prevalence of atherosclerosis was high in CKD population, more common in men and in the older age group. None of the CKD Stages had any significant co-relation with PVD. Femoral artery plaques identified by ultrasound are independently associated with lower eGFR. Femoral artery doppler ultrasonography will be a promising tool for identifying atherosclerosis in kidney disease in its earlier course.
JSS Academy of Higher Education & Research
Conflict of Interest
Atherosclerosis, chronic kidney disease, ultrasonography, peripheral vascular disease, plaque, intima media thickness.
Sogi D, Sarvi D, Goudar D, Karishetti D, Hattiholi D, Sarvi D.
Relationship Between Femoral Artery Intima-Media Thickness And Atherosclerosis In Patients With Chronic Kidney Disease- A One Year Hospital-Based Cross-Sectional Study.
Digital Journal of Clinical Medicine.
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