Evaluation of the role of prolactin to prevent diabetic retinopathy

Authors

Suliman A. Suliman, Tishreen University hospitalFollow

Author ORCID Identifier

ORCID ID

Corresponding Author

Suliman Suliman

www.Suliman00000@gmail.com

Abstract

Abstract:

Introduction: Diabetic retinopathy (DR) is a one of the long-term complications of DM and constitutes the leading cause of blindness in working-age individuals and affects a majority of diabetic patients by 20 years after disease onset.

Objective: The aim of this study it investigation of the potential role of prolactin in the prevention of Diabetic retinopathy.

Methods: The study was conducted on 90 diabetic patients who were divided into a group that included 37 patients without retinopathy and a group that included 27 patients with non-proliferative retinopathy and 26 patients with proliferative retinopathy who attended the Endocrinology clinic and Division at Tishreen University Hospital in Lattakia during the period from 2023 to 2024.

Results: Independent samples T-test analysis showed Significant decreased in prolactin level in diabetic patients with DR in comparison to diabetic patients without DR (p=0.0001). Person correlation showed a statistically significant inverse relationship between prolactin levels and Glycosylated hemoglobin levels between patient groups.

Conclusions: From this study it can be concluded that diabetic patients with retinopathy had lower level of prolactin and serum prolactin does seem to have protective role in diabetic retinopathy.

Publication Date

2024

Publisher

JSS Academy of Higher Education & Research

Keywords

Diabetic retinopathy, Prolactin, Glycosylated Haemoglobin

Recommended Citation

Suliman SA. Evaluation of the role of prolactin to prevent diabetic retinopathy. Digital Journal of Clinical Medicine. 2024; 6(2): -. doi: https://doi.org/10.55691/2582-3868.1186

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This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.