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Author ORCID Identifier

https://orcid.org/0000-0002-2314-8054

Corresponding Author

*DR. TANUKU V S R RAGHU

raghutanuku@gmail.com

Abstract

Hypertension ranks among the top ten causes of mortality, with around 4% attributed to hypertensive complications. High salt intake, Type 2 diabetes, smoking, elevated serum lipids, a sedentary lifestyle, a diet heavy in saturated fat, genetic predisposition, as well as stress are among the factors that contribute to hypertension. Hypertension affects about 1 billion people worldwide, with considerable differences between populations and ethnic groups [2]. The Framingham Heart Study indicates that a person's lifetime risk of developing hypertension is 90% if they are normotensive at age 55. According to the NHANES IV (4th National Health and Nutrition Examination Survey), the occurrence of hypertension in the US is 28.7%; it varies from 7.2% in people 18–39 years old to 65.4% in people 60 years of age and above. One important risk factor for peripheral vascular, kidney, and cardiovascular diseases, hypertension exhibits a robust, ongoing, and progressive association with these conditions. A person's risk of heart failure, coronary heart disease, and other cardiovascular events is doubled or quadrupled by hypertension, according to longitudinal data from the Framingham Heart Study, even in women. Aim and Objective: To investigate the patterns and prevalence of abnormalities related to cardiovascular risk factors in young patients with hypertension. To assess the impact of social, clinical, demographic, & socioeconomic factors on the lipid profile abnormalities in these patients. Materials and Methods: This cross-sectional study was conducted with patients diagnosed with hypertension at the outpatient department of Andhra Medical College and King George Hospital between July 2018 and October 2020. Study Group: The study included people who have newly diagnosed hypertension who were between the ages of thirty and forty. Patients on antihypertensive medication, those with secondary hypertension, newly diagnosed hypertensive patients with complications like ischemic heart disease, cerebrovascular accident, nephropathy, or retinopathy, or hypertensive patients who are diabetics or alcoholics were the exclusion criteria. Conclusion: Hypertension significantly elevates lipid levels and the prevalence of dyslipidemia. Gender, smoking, obesity, physical activity, and socioeconomic status influence these abnormalities. Future studies should include larger sample sizes and consider longitudinal designs to evaluate the effect of treatment for dyslipidemia on hypertension & vice versa.

Publication Date

2024

Publisher

JSS Academy of Higher Education & Research

Conflict of Interest

There is no conflict of interest disclosed by the authors

Keywords

Hypertension, Renin-Angiotensin System, Hyperinsulinism, Dyslipidemia, Renin

Word Count

2500

Comments

ORIGINAL RESEARCH : INTERNAL MEDICINE

The study entitled “Prevalence and Patterns of Cardiovascular Risk Factors in Young Hypertensive Patients” is a bonafied research done in The Department of General Medicine, Andhra Medical College, King George Hospital, Visakhapatnam , the college affiliated under Dr. N.T.R. University of Health Sciences, Vijayawada, Andhra Pradesh during 2018- 2020. This has got the approval the INSTITUTIONAL ETHICS COMMITTEE, KING GEORGE HOSPITAL, AMC vide REG NO: EC/NEW/ANST/2019/397. LETTER OF APPROVAL SERIAL NO: 158/IEC AMC/NOV/2020.

This is an observational study to assess the risk factors related to cardiovascular conditions and the underlying pathogenesis in causing hypertension in young hypertensives.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

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