Author ORCID Identifier
Abstract
Systematic reviews (SR) and meta-analyses (MA) are the highest level of evidence in the hierarchy of scientific evidence which aggregate data from various studies, offering a comprehensive overview of a particular topic. This approach reduces the influence of isolated studies that may have small sample sizes or unique biases, leading to more robust conclusions. By combining data from multiple studies, the overall sample size is increased enhancing the statistical power and precision of the results. The value of SR and MA is often compromised by the poor quality of the primary studies they include, which can lead to misleading conclusions. Many SRs were found flawed, redundant, or biased, which diminishes their reliability It is crucial to consider both the strengths and limitations of Systematic reviews to draw a valid conclusion. They must be critically appraised and updated regularly to maintain their validity as an invaluable tool in evidence-based medicine. Advanced analytical tools and supervised use of AI may add to the accuracy of SR and MA. By doing so, they can make more informed decisions that truly benefit patients and advance scientific understanding.
Publication Date
2024
Publisher
JSS Academy of Higher Education & Research
Conflict of Interest
None
Keywords
Evidence-based medicine, publication bias, research methodology, selection bias
Word Count
1005
Recommended Citation
Ahmad MM, Khan IA, Tiwari HC.
The Pros and Cons of Systematic Review and Meta-Analysis: Methodological Insights and Future Directions.
Digital Journal of Clinical Medicine.
2024;
6(4):
-.
doi:
https://doi.org/10.55691/2582-3868.1194
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Cover Page Footnote
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