Author ORCID Identifier
https://orcid.org/0009-0004-5426-9774
Abstract
Factor X deficiency is a rare coagulation disorder with a varied clinical spectrum. It can present at any age, but most severe cases present in childhood. There are no evidence-based management guidelines for the management of factor X deficiency due to limited literature. Detailed history, clinical examination and specialized tests (coagulation profile, mixing studies, factor assay) are required for the diagnosis of factor X deficiency. In this case report, we are discussing the case of a 1-month-old, 12-day-old female child who presented with the complaint of spontaneous bleeding from the nose since 1 day with no other bleeding manifestations from any other site. The coagulation study showed deranged PT and aPTT which were corrected after mixing studies. Factor X levels were low. Symptoms did not improve with topical agents, hence an FFP transfusion was started. Symptoms resolved, and the coagulation profile normalized after FFP transfusion.
Publication Date
Winter 1-7-2025
Publisher
JSS Academy of Higher Education & Research
Conflict of Interest
No conflict of interest
Keywords
Factor X, Mixing studies, Coagulation profile, FFP
Word Count
972
Recommended Citation
Kaur H, Das T, Wade P, Shaikh M.
A Case Report of Moderate Factor X Deficiency.
Digital Journal of Clinical Medicine.
2025;
7(2):
-.
doi:
https://doi.org/10.55691/2582-3868.1225
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.