Comparision of Buprenorphine versus Butorphanol as an adjuvant to intrathecal hyperbaric bupivacaine for elective infraumbilical surgeries : A randomised control study at a tertiary care hospital, Mandya

Authors

• Surabhi C A, Mandya Institute Of Medical SciencesFollow
• Dr. Kiran A V. Associate professor, Mandya Institute of Medical Sciences, MandyaFollow
• Dr. Shivakumar G Pofessor and HOD, Mandya Institute of Medical Sciences, MandyaFollow
• Umesh N P, Mandya Institute Of Medical SciencesFollow

Author ORCID Identifier

https://orcid.org/0009-0004-7723-7249

https://orcid.org/0000-0001-9568-2929

https://orcid.org/0009-0000-7083-5482

https://orcid.org/0009-0001-4316-9346

Corresponding Author

Dr Umesh N P

drumeshnp@gmail.com

Abstract

Introduction: Spinal anaesthesia is the most popularly performed procedure in the field of anaesthesiology. Hyperbaric bupivacaine, the local anaesthetic most commonly used, has limitation as its effect lasts only for 1.5-2 hours. Hence a lot of adjuvants have been tried to enhance the analgesic effect of bupivacaine.^[2] Opioids remain the mainstay among the various adjuvants to local anesthetics in spinal anaesthesia primarily by virtue of its various properties such as reducing the dose of local anaesthetic, minimizing side effects, and prolonging the duration of anaesthesia.^[3]

Aim: This study aims to compare the sensory and motor characteristics and, post operative pain relief between buprenorphine and butorphanol as an adjuvant to intrathecal 0.5% hyperbaric bupivacaine including adverse effects of the study drugs in patients undergoing infraumbilical surgeries under spinal anaesthesia.

Materials and methods: Written informed consent was obtained from research participants. A computer-generated random number was used to divide the number of patients who met the inclusion criteria into two groups. Group BT patients recieved 3mL (15mg) of 0.5% hyperbaric bupivacaine along with 25mcg butorphanol. Group BN patients received 30mcg of buprenorphine together with 3 ml of 0.5% hyperbaric bupivacaine

Results: Butorphanol produced earlier onset of sensory and motor blockade as well as a longer time for first analgesic request when compared with buprenorphine at our study doses.

Conclusion: Butorphanol produced earlier onset of sensory and motor blockade as well as a longer time for first analgesic request when compared with buprenorphine at our study doses.

Keywords: Sub-arachnoid block, butorphanol, buprenorphine, rescue analgesic

Publication Date

2025

Publisher

JSS Academy of Higher Education & Research

Conflict of Interest

none

Keywords

Sub-arachnoid block, butorphanol, buprenorphine, rescue analgesic

Word Count

2722

Recommended Citation

C A S, A V. D Associate professor, G D Pofessor and HOD, N P U. Comparision of Buprenorphine versus Butorphanol as an adjuvant to intrathecal hyperbaric bupivacaine for elective infraumbilical surgeries : A randomised control study at a tertiary care hospital, Mandya. Digital Journal of Clinical Medicine. 2025; 8(1): -. doi: https://doi.org/10.55691/2582-3868.1284

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