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International Journal of Health and Allied Sciences

Abstract

Background: Dyslipidemias, a disorder of lipid metabolism, is widely established as an independent major and modifiable risk factor of cardiovascular disease (CVD). The conditions are common worldwide and a leading cause of death in India, and has even riven the age bar swaying in young people too. The significant effect of an increase in dyslipidemias depends on diabetes and hypertension. Nutraceuticals, derived from food sources serve as an alternative therapy for the management of dyslipidemia. India is home to multitudinous medicinal plants, of which many remain underutilized. Murraya Koenigii (curry leaf) and Trigonella foenum-graecum (fenugreek leaves) are well-proven as good sources of nutraceutical and functional foods. Objectives: To study the effect of fenugreek and curry leaves powder on dyslipidemia and also the dietary habits of dyslipidemic subjects. Materials and Methods: 31 subjects aged between 40-70 years were recruited based on inclusion and exclusion criteria, and grouped into group 1(hypertensive with dyslipidemia), group 2 (diabetic with dyslipidemia), and group 3 (only dyslipidemia) supplemented with the mixture of fenugreek and curry leaf powder for 3 months. Results: Reduction in total cholesterol and triglyceride levels were observed in group 2 (DM+DLP) and group 1 (HTN+DLP) i.e 221.2±29 and 193±72.4 respectively. The HDL levels increased in all three groups. Reduced VLDL and FBS levels were observed in all three groups. Conclusion: Our findings showed that fenugreek and curry leaf powder supplementation, as a phenolic-rich herb can be effective in the reduction of some lipid profiles in dyslipidemic patients suggesting their potential neutraceutical role in treating CVD.

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