International Journal of Health and Allied Sciences


Background: Regenerative endodontic treatment aims to relieve symptoms and maintain root development and regeneration of pulp tissue. This study aimed to retrospectively examine and compare the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in the regenerative endodontic treatment (RET) of immature necrotic teeth in terms of clinical and radiographic treatment results.

Materials and Methods: This study included patients who underwent Regenerative Endodontic Treatment (RET) at Selcuk University Faculty of Dentistry between 2014 and 2019, totalling 38 cases. After apical bleeding is induced into the canal, PRP was utilized in 16 cases, while PRF was employed in 22 cases during the treatments. The changes in root length and dentin thickness were calculated by measuring the radiographs with the help of Image J software. The success rates of the treatments were evaluated in the range of 0-3 points based on the scoring index of Bezgin et al. Changes in root length and dentin thickness, apical closure, and success score were compared statistically in PRP and PRF treatment methods.

Results: There was no statistically significant difference between the group who had treatment with PRP and those who had treatment with PRF in terms of apical closure, root length increase, and success scoring, but there was a significant difference in terms of increased dentin thickness.

Conclusions: The use of PRP and PRF in RET showed similar results in terms of treatment success. Both treatment groups showed an increase in dentin thickness and root length.