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International Journal of Health and Allied Sciences

Abstract

Antimicrobial resistance (AMR) is a major global health problem. The growing number of antibiotic-resistant microbes needs the development of novel antibiotics. Nanotechnology shows potential for overcoming bacterial resistance. Nanoparticles, particularly those around 100 nm, display higher antibacterial activity by using methods that differ from traditional antibiotics. When particle size reduces, materials such as zinc and silver improve their antibacterial action. There are several techniques to evaluate nanoparticle antibacterial activity, each having merits and downsides. This study critically evaluates selected literature, identifies bactericidal mechanisms, and discusses assessment procedures, emphasizing the importance of innovative approaches to bacterial infections.

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